Oocyte Cryopreservation Abroad At Low Cost - Oocyte Cryopreservation

Sperm and embryos (fertilized eggs) have been successfully frozen for decades for the purposes of fertility preservation and donation for men and couples. Although both sperm and embryo cryopreservation have become commonplace, oocyte preservation or the freezing of unfertilized oocytes (or eggs) for similar applications in women has not historically delivered the acceptable success rates necessary to drive adoption across the board.

Unlike sperm and embryos, oocytes did not survive the freeze/thaw aspects of the Egg-freezing process well primarily because the egg is the largest cell in the human body and comprised mostly of water. The water inside the cell forms ice crystals that destroy the egg during the traditional egg freezing process. Prior to 2002, the success rate of live births from frozen eggs was 1-3% globally, with few babies born from frozen eggs over decades of attempts. Fortunately, a number of advances in our knowledge of oocyte preservation, oocyte physiology and laboratory techniques are rapidly changing this fertility extension dream into a reality...

Oocyte Cryopreservation Techniques and Technologies

Given the magnitude of the need, clinicians around the world have raced to develop a Oocyte cryopreservation technique for successful egg-freezing, and, beginning in 2002, promising results ranging from 20-40% successful pregnancy rate (on par with a woman’s natural peak fertility rate) were published. The key difference over previous techniques was the change in cryoprotectants used to protect the egg during the egg freezing process. Cryoprotectant acts as an “anti-freeze” to protect the delicate eggs as the temperature drops. Before attempting to understand how our ability to cryopreserve unfertilized eggs has been achieved, it is important to understand how sperm and embryo (fertilized oocytes) cryopreservation has long been commonplace...

Oocyte Cryopreservation Research Study Conclusions

To date, we are just reaching a time where it is becoming feasible for mature oocyte cryopreservation. These are harvested after taking fertility medications to induce the maturation of a number of mature oocytes. Women of this generation want more options and power when it comes making life decisions and plans. This is an exciting next step in the long line of developments in the field of women’s reproductive health – on par with the introduction of the birth control pill....

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